Journal: Journal of Inflammation Research
Article Title: Inflammation-Related Gene ADH1A Regulates the Polarization of Macrophage M1 and Influences the Malignant Progression of Gastric Cancer
doi: 10.2147/JIR.S452670
Figure Lengend Snippet: ADH1A affects the malignant progression of GC through the cGMP-PKG signaling pathway. ( A ) Results of ssGSEA of ADH1A; ( B ) The expression levels of PKG1, PKG2, pVASP and VASP protein; ( C ) The expression of cGMP; ( D ) Detection of cell activity; ( E ) Detection of cell proliferation; ( F ) Cell migration ability; ( G ) Cell invasion ability; ( H ) Apoptosis level; ( I ) The expression of IL-6 and IFN-γ; ( J ) The expression of CCL5 and CSF2.
Article Snippet: Antibodies included ADH1A (Invitrogen, PA5-78730), PKG1 (proteintech, 21646-1-AP), PKG2 (proteintech, 55138-1-AP), pVASP (cell signaling technology, 3111), and VASP (cell signaling technology, 3132).
Techniques: Expressing, Activity Assay, Migration